Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival. (Q37959319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22105567%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival (English)

1 reference

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17 January 2020

main subject

endoplasmic reticulum

0 references

1 reference

4

1 reference

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17 January 2020

author name string

James D Johnson

series ordinal

1

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17 January 2020

Michael J Bround

series ordinal

2

1 reference

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17 January 2020

Sarah A White

series ordinal

3

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17 January 2020

publication date

22 November 2011

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17 January 2020

1 reference

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17 January 2020

volume

249 Suppl 1

1 reference

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17 January 2020

page(s)

S49-58

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Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.

17 January 2020

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Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

21 January 2018

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21 January 2018

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Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

21 January 2018

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Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

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First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx

21 January 2018

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Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

21 January 2018

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Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

21 January 2018

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21 January 2018

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21 January 2018

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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

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Topology of superoxide production from different sites in the mitochondrial electron transport chain

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21 January 2018

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Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin.

21 January 2018

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Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance

21 January 2018

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Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

21 January 2018

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Uncoupling protein-2 modulates myocardial excitation-contraction coupling.

21 January 2018

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

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The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

21 January 2018

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A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro

21 January 2018

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Presenilins are essential for regulating neurotransmitter release

21 January 2018

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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism

21 January 2018

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Calcium - a life and death signal

21 January 2018

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Mitochondrial oxidative stress and cell death in astrocytes--requirement for stored Ca2+ and sustained opening of the permeability transition pore

21 January 2018

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12 December 2020

Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression

1 reference

12 December 2020

Regulation of mammalian ryanodine receptors

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12 December 2020

Endoplasmic reticulum stress and diabetes mellitus.

1 reference

12 December 2020

Mitochondrial modulation of Ca2+ -induced Ca2+ -release in rat sensory neurons

1 reference

12 December 2020

Ruthenium red modifies the cardiac and skeletal muscle Ca(2+) release channels (ryanodine receptors) by multiple mechanisms

1 reference

12 December 2020

High density distribution of endoplasmic reticulum proteins and mitochondria at specialized Ca2+ release sites in oligodendrocyte processes

1 reference

12 December 2020

Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

1 reference

12 December 2020

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

1 reference

12 December 2020

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

1 reference

12 December 2020

The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions

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12 December 2020

Intracellular calcium-release channels: regulators of cell life and death

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12 December 2020

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

1 reference

12 December 2020

Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion

1 reference

12 December 2020

Caspase and calpain substrates: roles in synaptic plasticity and cell death

1 reference

12 December 2020

Mitochondria suppress local feedback activation of inositol 1,4, 5-trisphosphate receptors by Ca2+

1 reference

12 December 2020

Function- and agonist-specific Ca2+ signalling: the requirement for and mechanism of spatial and temporal complexity in Ca2+ signals

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12 December 2020

Unlocking the secrets of the pancreatic beta cell: man and mouse provide the key.

1 reference

12 December 2020

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

1 reference

12 December 2020

The organisation and functions of local Ca(2+) signals.

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12 December 2020

Suppressed insulin signaling and increased apoptosis in CD38-null islets

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12 December 2020

Evidence of functional ryanodine receptor involved in apoptosis of prostate cancer (LNCaP) cells

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12 December 2020

Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion

1 reference

12 December 2020

10.1007/S00709-011-0349-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22105567%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference