Receptor-mediated endocytosis and brain delivery of therapeutic biologics (Q38120524)

29 August 2017

Receptor-mediated endocytosis and brain delivery of therapeutic biologics (English)

1 reference

29 August 2017

Guangqing Xiao

1

1 reference

PMC publication ID

3693099

29 August 2017

Liang-Shang Gan

series ordinal

2

1 reference

29 August 2017

11 June 2013

1 reference

International Journal of Cell Biology

29 August 2017

1 reference

29 August 2017

2013

1 reference

29 August 2017

703545

1 reference

Creative Commons Attribution 3.0 Unported

29 August 2017

start time

1 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

1 reference

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Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood-brain barrier

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism

14 September 2017

1 reference

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Genetic engineering of IgG-glucuronidase fusion proteins

14 September 2017

1 reference

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Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier

28 September 2017

1 reference

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28 September 2017

1 reference

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28 September 2017

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Receptor-mediated abeta amyloid antibody targeting to Alzheimer's disease mouse brain

23 June 2018

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Genetic engineering of a bifunctional IgG fusion protein with iduronate-2-sulfatase

23 June 2018

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Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse.

23 June 2018

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Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor.

23 June 2018

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Requirement for a beta 2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice.

23 June 2018

1 reference

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Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo

23 June 2018

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Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo models

23 June 2018

1 reference

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Investigation of the role of FcγR and FcRn in mAb distribution to the brain

23 June 2018

1 reference

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Safety, pharmacokinetics, and activity of GRN1005, a novel conjugate of angiopep-2, a peptide facilitating brain penetration, and paclitaxel, in patients with advanced solid tumors

31 August 2018

1 reference

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A cascade targeting strategy for brain neuroglial cells employing nanoparticles modified with angiopep-2 peptide and EGFP-EGF1 protein

31 August 2018

1 reference

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Olfactory ensheathing cells as putative host cells for Streptococcus pneumoniae: evidence of bacterial invasion via mannose receptor-mediated endocytosis

31 August 2018

1 reference

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Identification and design of peptides as a new drug delivery system for the brain

31 August 2018

1 reference

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Functional characterization of the brain-to-blood efflux clearance of human amyloid-beta peptide (1-40) across the rat blood-brain barrier

31 August 2018

1 reference

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Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn).

31 August 2018

1 reference

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An engineered human IgG1 antibody with longer serum half-life.

31 August 2018

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IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

31 August 2018

1 reference

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The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells

31 August 2018

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Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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Effect of Target Dynamics on Pharmacokinetics of a Novel Therapeutic Antibody against the Epidermal Growth Factor Receptor: Implications for the Mechanisms of Action

31 August 2018

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12 December 2020

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1 reference

12 December 2020

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Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1

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Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells

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Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences

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[The neonatal receptor Fc gamma(FcRn)--structure and function]

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Unique single‐domain antigen binding fragments derived from naturally occurring camel heavy‐chain antibodies

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Localization of the site of the IgG molecule that regulates maternofetal transmission in mice

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Identifiers

DOI

10.1155/2013/703545

1 reference

29 August 2017

1 reference

PMC publication ID

3693099

29 August 2017

PubMed publication ID

23840214

1 reference

PMC publication ID

3693099