Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation (Q38328865)

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English	Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

phosphorylation

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author name string

W Spencer

1

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Europe PubMed Central

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2 September 2017

H Kwon

2

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2 September 2017

P Crépieux

3

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2 September 2017

N Leclerc

4

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2 September 2017

R Lin

5

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2 September 2017

J Hiscott

6

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2 September 2017

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1 January 1999

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Europe PubMed Central

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2 September 2017

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Europe PubMed Central

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2 September 2017

18

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2 September 2017

2

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Europe PubMed Central

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2 September 2017

495-505

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Europe PubMed Central

PubMed publication ID

2 September 2017

Motility of intracellular particles in rat fibroblasts is greatly enhanced by phorbol ester and by over-expression of normal p21N-ras

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How does taxol stabilize microtubules?

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

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NF-kappa B: ten years after

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Function and activation of NF-kappa B in the immune system

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Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis

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The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

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Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

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I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain

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Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.

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Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo

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Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

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Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes.

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Biological specificity and measurable physical properties of cell surface receptors and their possible role in signal transduction through the cytoskeleton

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Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes

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Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

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Control of signal transduction and morphogenesis by Ras.

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Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP

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Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

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Focal adhesion formation is associated with secretion of allergic mediators

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Identification of Tumor-Specific Paclitaxel (Taxol)-Responsive Regulatory Elements in the Interleukin-8 Promoter

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Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

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Binding of CD44 to hyaluronic acid can be induced by multiple signals and requires the CD44 cytoplasmic domain

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Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB

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Phorbol esters and PKC signaling regulate proliferation, vimentin cytoskeleton assembly and glutamine synthetase activity of chick embryo cerebrum astrocytes in culture

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Microfilament assembly is required for anti-IgM dependent MAPK and p90rsk activation in human B lymphocytes.

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Differential Effect of Activators of Protein Kinase C on Cytoskeletal Changes in Mouse and Hamster Eggs

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Identification and characterization of an IkappaB kinase

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Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions

1 reference

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Association of mitogen-activated protein kinase with the microtubule cytoskeleton

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based on heuristic

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In vivo control of NF-kappa B activation by I kappa B alpha.

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Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

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Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

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10.1038/SJ.ONC.1202335

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Europe PubMed Central

PubMed publication ID

2 September 2017

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PubMed publication ID

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Europe PubMed Central

PubMed publication ID

2 September 2017

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