A Defect in the p53 Response Pathway Induced by de Novo Purine Synthesis Inhibition (Q38349842)

2 September 2017

title

A defect in the p53 response pathway induced by de novo purine synthesis inhibition (English)

1 reference

2 September 2017

A Defect in the p53 Response Pathway Induced by de Novo Purine Synthesis Inhibition (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

15 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

15 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

15 March 2024

author name string

Julie L. Bronder

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517211

15 March 2024

Richard G. Moran

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517211

15 March 2024

language of work or name

English

0 references

publication date

29 September 2003

1 reference

full work available at URL

2 September 2017

http://www.jbc.org/content/278/49/48861.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517211

https://api.elsevier.com/content/article/PII:S0021925820756528?httpAccept=text/xml

15 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

https://api.elsevier.com/content/article/PII:S0021925820756528?httpAccept=text/plain

15 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

https://syndication.highwire.org/content/doi/10.1074/jbc.M304844200

15 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M304844200

Journal of Biological Chemistry

15 March 2024

published in

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2 September 2017

volume

278

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2 September 2017

issue

49

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2 September 2017

page(s)

48861-48871

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UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

2 September 2017

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p21 is a universal inhibitor of cyclin kinases

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p53 accumulates but is functionally impaired when DNA synthesis is blocked

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Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase

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Phase I study of (6R)-5,10-dideazatetrahydrofolate: a folate antimetabolite inhibitory to de novo purine synthesis

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In vivo cross-linking and immunoprecipitation for studying dynamic Protein:DNA associations in a chromatin environment

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A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

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Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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DNA damage activates p53 through a phosphorylation-acetylation cascade

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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

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Acetylation of histones and transcription-related factors

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Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

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Regulation of p53 function and stability by phosphorylation

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DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation

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ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

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15 March 2024

Identifiers

1 reference

2 September 2017

1 reference