Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. (Q38343552)

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25 December 2019

title

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells (English)

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25 December 2019

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acute myeloid leukemia

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6

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25 December 2019

Martin Ruthardt

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25 December 2019

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Carsten Müller-Tidow

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25 December 2019

author name string

Björn Steffen

2

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Thomas Cauvet

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Lara Tickenbrock

4

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25 December 2019

Ping Ji

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25 December 2019

Bülent Sargin

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Gabriele Köhler

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Matthias Stelljes

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Elena Puccetti

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Sven deVos

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25 December 2019

Scott W Hiebert

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H Phillip Koeffler

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Wolfgang E Berdel

15

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Hubert Serve

16

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25 December 2019

language of work or name

English

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publication date

1 April 2004

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Molecular and Cellular Biology

25 December 2019

published in

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volume

24

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issue

7

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25 December 2019

page(s)

2890-2904

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

25 December 2019

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6 September 2017

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6 September 2017

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c-Myc is a critical target for c/EBPalpha in granulopoiesis.

6 September 2017

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AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

6 September 2017

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Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function

6 September 2017

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Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

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Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia

6 September 2017

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AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

1 reference

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Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent

6 September 2017

1 reference

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

6 September 2017

1 reference

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The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

14 September 2017

1 reference

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gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

14 September 2017

1 reference

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Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

14 September 2017

1 reference

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

14 September 2017

1 reference

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WNT signaling modulates the diversification of hematopoietic cells.

27 September 2017

1 reference

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The aberrant fusion proteins PML-RAR alpha and PLZF-RAR alpha contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia

27 September 2017

1 reference

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Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.

27 September 2017

1 reference

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Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways

27 September 2017

1 reference

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Differential expression of Id genes in multipotent myeloid progenitor cells: Id-1 is induced by early-and late-acting cytokines while Id-2 is selectively induced by cytokines that drive terminal granulocytic differentiation

27 September 2017

1 reference

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High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein

27 September 2017

1 reference

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Oncogenic transcription factors in the human acute leukemias

27 September 2017

1 reference

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The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

23 June 2018

1 reference

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The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells

23 June 2018

1 reference

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The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

31 August 2018

1 reference

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Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.

31 August 2018

1 reference

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Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

31 August 2018

1 reference

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RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

31 August 2018

1 reference

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Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer

31 August 2018

1 reference

12 December 2020

PML is a target gene of beta-catenin and plakoglobin, and coactivates beta-catenin-mediated transcription

1 reference

12 December 2020

Id2 expression increases with differentiation of human myeloid cells

1 reference

12 December 2020

Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences

1 reference

12 December 2020

10.1128/MCB.24.7.2890-2904.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15024077%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15024077%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

15024077

1 reference