E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest (Q39404546)

11 September 2017

title

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest (English)

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11 September 2017

5

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Hendrik Gerard Stunnenberg

11 September 2017

series ordinal

4

object named as

Hendrik G Stunnenberg

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11 September 2017

6

Daniel S Peeper

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11 September 2017

Benjamin D Rowland

1

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11 September 2017

Serguei G Denissov

series ordinal

2

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11 September 2017

Sirith Douma

series ordinal

3

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11 September 2017

publication date

1 July 2002

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11 September 2017

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11 September 2017

volume

2

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11 September 2017

issue

1

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11 September 2017

page(s)

55-65

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The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein

11 September 2017

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7 January 2021

p14ARF links the tumour suppressors RB and p53.

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7 January 2021

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

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7 January 2021

New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2

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7 January 2021

Requirements for cell cycle arrest by p16INK4a

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7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

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7 January 2021

E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

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7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

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7 January 2021

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

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7 January 2021

Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

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7 January 2021

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

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7 January 2021

Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.

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7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

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7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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7 January 2021

E2F is required to prevent inappropriate S-phase entry of mammalian cells

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7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

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7 January 2021

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

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7 January 2021

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

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7 January 2021

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter

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7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

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7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

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7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

The role of cyclin E in cell proliferation, development and cancer

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7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

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7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

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7 January 2021

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

1 reference

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7 January 2021

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

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7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

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7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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7 January 2021

p19ARF targets certain E2F species for degradation.

1 reference

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7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

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7 January 2021

Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

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7 January 2021

Analysis of chromatin structure by in vivo formaldehyde cross-linking.

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7 January 2021

p19ARF links the tumour suppressor p53 to Ras

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7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

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7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

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7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

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7 January 2021

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

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7 January 2021

The transcription factor E2F-1 is a downstream target of RB action

1 reference

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7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

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7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

The transcription factor E2F-1 mediates the autoregulation of RB gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Cellular senescence: mitotic clock or culture shock?

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

1 reference

7 January 2021

Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

p53-independent functions of the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

The E2F1-3 transcription factors are essential for cellular proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900085-5

7 January 2021

10.1016/S1535-6108(02)00085-5

Identifiers

DOI

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release_bt7hjaarengm3kcx5oalftra5y

11 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bt7hjaarengm3kcx5oalftra5y

24 November 2022

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