Insulin-activated Akt rescues Aβ oxidative stress-induced cell death by orchestrating molecular trafficking. (Q39533821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Insulin-activated Akt rescues Aβ oxidative stress-induced cell death by orchestrating molecular trafficking (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Daniela Giacomazza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Valeria Vetri

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Rita Carrotta

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Pier Luigi San Biagio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Marta Di Carlo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

5

Valeria Militello

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

publication date

8 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

832-843

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21624038%20AND%20SRC:MED&resulttype=core&format=json

Regional Concentrations of Insulin in the Rat Brain*

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Immunocytochemical Detection of Insulin in Rat Hypothalamus and Its Possible Uptake from Cerebrospinal Fluid*

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin and insulin-like growth factors in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Immunocytochemical detection of insulin receptor substrate-1 (IRS-1) in rat brain: colocalization with phosphotyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin receptor substrate-1 (IRS-1) expression in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Aging, energy, and oxidative stress in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Mitochondria take center stage in aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

From mice to men: insights into the insulin resistance syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Bidirectional regulation of p38 kinase and c-Jun N-terminal protein kinase by insulin-like growth factor-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

FOXO3A regulates peroxiredoxin III expression in human cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin and neurodegenerative disease: shared and specific mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin promotes survival of amyloid-beta oligomers neuroblastoma damaged cells via caspase 9 inhibition and Hsp70 upregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

FOXO transcription factors at the interface between longevity and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Insulin can block apoptosis by decreasing oxidative stress via phosphatidylinositol 3-kinase- and extracellular signal-regulated protein kinase-dependent signaling pathways in HepG2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Rescue of alpha-synuclein cytotoxicity by insulin-like growth factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Oxidative damage to RNA in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Mitochondria and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Amyloid precursor protein-mediated free radicals and oxidative damage: implications for the development and progression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

On the paradox of ion channel blockade and its benefits in the treatment of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Pouring oil into the fire? On the conundrum of the beneficial effects of NMDA receptor antagonists in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Reactive oxygen species and synaptic plasticity in the aging hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Role of insulin and insulin receptor in learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X

Intraneuronal -Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00724.X