Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase (Q39918354)

15 September 2017

Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase (English)

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15 September 2017

Franck Duong

1

1 reference

15 September 2017

language of work or name

English

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publication date

1 September 2003

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15 September 2017

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15 September 2017

22

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15 September 2017

17

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15 September 2017

4375-4384

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describes a project that uses

15 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC202361/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ring-like pore structures of SecA: implication for bacterial protein-conducting channels

1 reference

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Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase

22 September 2017

1 reference

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The general protein secretory pathway: phylogenetic analyses leading to evolutionary conclusions

22 September 2017

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Bacterial secretome: the assembly manual and operating instructions (Review).

22 September 2017

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Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA

22 September 2017

1 reference

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Dissociation of the dimeric SecA ATPase during protein translocation across the bacterial membrane

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Three-dimensional structure of the bacterial protein-translocation complex SecYEG

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Complex behavior in solution of homodimeric SecA.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The SecYEG preprotein translocation channel is a conformationally dynamic and dimeric structure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Projection structure and oligomeric properties of a bacterial core protein translocase

22 September 2017

1 reference

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Evaluating the oligomeric state of SecYEG in preprotein translocase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecYEG assembles into a tetramer to form the active protein translocation channel

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

In vivo cross-linking of the SecA and SecY subunits of the Escherichia coli preprotein translocase

22 September 2017

1 reference

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Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme

22 September 2017

1 reference

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Both an N-terminal 65-kDa domain and a C-terminal 30-kDa domain of SecA cycle into the membrane at SecYEG during translocation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

An improved assay for nanomole amounts of inorganic phosphate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Topology of the integral membrane form of Escherichia coli SecA protein reveals multiple periplasmically exposed regions and modulation by ATP binding.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

A high concentration of SecA allows proton motive force-independent translocation of a model secretory protein into Escherichia coli membrane vesicles.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecA protein needs both acidic phospholipids and SecY/E protein for functional high-affinity binding to the Escherichia coli plasma membrane

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Fluorescence resonance energy transfer analysis of protein translocase. SecYE from Thermus thermophilus HB8 forms a constitutive oligomer in membranes.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecY-SecY and SecY-SecG contacts revealed by site-specific crosslinking

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The ATPase domain of SecA can form a tetramer in solution.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Mapping the sites of interaction between SecY and SecE by cysteine scanning mutagenesis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Effect of divalent cations on the ATPase activity of Escherichia coli SecA.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The protease-protected 30 kDa domain of SecA is largely inaccessible to the membrane lipid phase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Identification of a region of interaction between Escherichia coli SecA and SecY proteins.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecA, the peripheral subunit of the Escherichia coli precursor protein translocase, is functional as a dimer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

The C terminus of SecA is involved in both lipid binding and SecB binding.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=202361

Escherichia coli SecA shape and dimensions

20 August 2018

1 reference

12 December 2020

The bacterial SecY/E translocation complex forms channel-like structures similar to those of the eukaryotic Sec61p complex

1 reference

12 December 2020

Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli

1 reference

12 December 2020

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

1 reference

12 December 2020

The carboxyl-terminal region is essential for Sec-A dimerization

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG418

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

12941690

1 reference