Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. (Q30453215)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12486000%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression (English)

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15 December 2019

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2

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15 December 2019

Martin A Schwartz

7

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15 December 2019

author name string

Eleni Tzima

1

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15 December 2019

William B Kiosses

3

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15 December 2019

Samih A Mohamed

4

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15 December 2019

Song Li

5

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15 December 2019

Shu Chien

6

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15 December 2019

language of work or name

English

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publication date

1 December 2002

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15 December 2019

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15 December 2019

volume

21

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15 December 2019

issue

24

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15 December 2019

page(s)

6791-6800

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Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

15 December 2019

cites work

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Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

20 June 2018

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Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity

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Activation of Rac and Cdc42 by integrins mediates cell spreading

20 June 2018

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Effects of mechanical forces on signal transduction and gene expression in endothelial cells

20 June 2018

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Activation of the NF-kappa B and I kappa B system in smooth muscle cells after rat arterial injury. Induction of vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

20 June 2018

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Multiple cis-elements mediate shear stress-induced gene expression.

20 June 2018

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20 June 2018

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20 June 2018

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Pulsatile and steady flow induces c-fos expression in human endothelial cells

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression

20 June 2018

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Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

20 June 2018

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Hemodynamic forces are complex regulators of endothelial gene expression.

20 June 2018

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20 June 2018

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

20 June 2018

1 reference

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Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions

20 June 2018

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20 June 2018

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Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells

20 June 2018

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20 June 2018

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An inducible transcription factor activates expression of human immunodeficiency virus in T cells

20 June 2018

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Leukocyte adhesion to endothelium in inflammation

20 June 2018

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Actin microfilament dynamics in locomoting cells

20 June 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

20 June 2018

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Syringe loading introduces macromolecules into living mammalian cell cytosol

20 June 2018

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Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells

20 June 2018

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Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

26 November 2018

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Fluid shear stress activation of IkappaB kinase is integrin-dependent

26 November 2018

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Elementary mechanics of the endothelium of blood vessels

26 November 2018

1 reference

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Fluid shear stress modulates surface expression of adhesion molecules by endothelial cells

26 November 2018

1 reference

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Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow

26 November 2018

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12 December 2020

Flow effects on prostacyclin production by cultured human endothelial cells

1 reference

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Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion

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12 December 2020

Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force

1 reference

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Shear stress induces spatial reorganization of the endothelial cell cytoskeleton

1 reference

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Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS

1 reference

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Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors

1 reference

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Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress

1 reference

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Endothelial gene regulation by laminar shear stress

1 reference

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Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter

1 reference

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Reactive oxygen species are involved in shear stress-induced intercellular adhesion molecule-1 expression in endothelial cells

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Identifiers

DOI

10.1093/EMBOJ/CDF688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12486000%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12486000%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

12486000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12486000%20AND%20SRC:MED&resulttype=core&format=json