Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations (Q33577711)

28 July 2017

title

Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations (English)

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28 July 2017

Ramin Radpour

2

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Per Lenner

6

object named as

Per Lenner

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28 July 2017

Zeinab Barekati

1

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28 July 2017

Corina Kohler

3

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28 July 2017

Bei Zhang

4

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28 July 2017

Paolo Toniolo

5

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28 July 2017

Qing Lv

7

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28 July 2017

Hong Zheng

8

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28 July 2017

Xiao Yan Zhong

9

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28 July 2017

publication date

12 May 2010

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28 July 2017

published in

Human Molecular Genetics

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28 July 2017

volume

19

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28 July 2017

issue

15

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28 July 2017

page(s)

2936-2946

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Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

28 July 2017

cites work

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Identification of a putative p53 binding sequence within the human mitochondrial genome

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The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells.

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Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

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Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

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Somatic mutations of the mitochondrial genome in human colorectal tumours

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Mitochondrial D-loop mutation is a common event in colorectal cancers with p53 mutations.

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Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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Somatic mutations in the p53 gene and prognosis in breast cancer: a meta-analysis

21 January 2018

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Mitochondrial regulation of cancer associated nuclear DNA methylation

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Infrequent mutations in the PTEN/MMAC1 gene among primary breast cancers

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

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Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

21 January 2018

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PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

21 January 2018

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

21 January 2018

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Methylation profiles of 22 candidate genes in breast cancer using high-throughput MALDI-TOF mass array.

21 January 2018

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Gene silencing in cancer in association with promoter hypermethylation

21 January 2018

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Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

21 January 2018

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Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer

21 January 2018

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Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms.

21 January 2018

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Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer

21 January 2018

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Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

21 January 2018

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Levels of plasma circulating cell free nuclear and mitochondrial DNA as potential biomarkers for breast tumors.

21 January 2018

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Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

21 January 2018

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Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients.

21 January 2018

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Simultaneous isolation of DNA, RNA, and proteins for genetic, epigenetic, transcriptomic, and proteomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ199

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ199

MethPrimer: designing primers for methylation PCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ199

Simultaneous quantitative assessment of circulating cell-free mitochondrial and nuclear DNA by multiplex real-time PCR.

21 January 2018

1 reference

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Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDQ199

1 reference

release_2bwzvejdpnflhczerpqiumqrwy

28 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2bwzvejdpnflhczerpqiumqrwy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference