Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets (Q33747423)

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scientific article published on December 1, 2010

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English	Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets	scientific article published on December 1, 2010

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

title

Grand challenge commentary: Accessing new chemical space for 'undruggable' targets (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets (English)

1 reference

stated in

Crossref

DOI

10.1038/NCHEMBIO.479

reference URL

https://api.crossref.org/works/10.1038/NCHEMBIO.479

retrieved

27 August 2024

main subject

small molecule libraries

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21079589

retrieved

27 August 2024

author name string

Sivaraman Dandapani

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

Lisa A. Marcaurelle

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21079589

retrieved

27 August 2024

language of work or name

English

1 reference

stated in

National Center for Biotechnology Information

PubMed publication ID

21079589

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21079589

retrieved

27 August 2024

publication date

1 December 2010

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

full work available at URL

http://www.nature.com/articles/nchembio.479.pdf

file format

Portable Document Format

1 reference

stated in

Crossref

DOI

10.1038/NCHEMBIO.479

reference URL

https://api.crossref.org/works/10.1038/NCHEMBIO.479

retrieved

27 August 2024

http://www.nature.com/articles/nchembio.479

1 reference

stated in

Crossref

DOI

10.1038/NCHEMBIO.479

reference URL

https://api.crossref.org/works/10.1038/NCHEMBIO.479

retrieved

27 August 2024

published in

Nature Chemical Biology

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

volume

6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

issue

12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

page(s)

861-863

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stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

cites work

Enhancements of screening collections to address areas of unmet medical need: an industry perspective

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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Spiroindolones, a potent compound class for the treatment of malaria

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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Escape from flatland: increasing saturation as an approach to improving clinical success

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PubMed

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12 December 2020

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Integrating cheminformatic analysis in combinatorial chemistry

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

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12 December 2020

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A small molecule that binds Hedgehog and blocks its signaling in human cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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inferred from PubMed ID database lookup

Current strategies for diversity-oriented synthesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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On the potential of natural products in the discovery of pharma leads: a case for reassessment

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12 December 2020

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Diversity-oriented synthesis of a cytisine-inspired pyridone library leading to the discovery of novel inhibitors of Bcl-2.

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12 December 2020

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Diversity-oriented synthesis: exploring the intersections between chemistry and biology

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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Probing the probes: fitness factors for small molecule tools

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

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inferred from PubMed ID database lookup

The interdependence between screening methods and screening libraries.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21079589

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Genomics and Genetics in Drug Discovery and Development

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCHEMBIO.479

retrieved

7 January 2021

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Identifiers

DOI

10.1038/NCHEMBIO.479

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

PubMed publication ID

21079589

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21079589

retrieved

29 July 2017

 

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