PTEN regulates Mdm2 expression through the P1 promoter (Q44848220)

6 December 2017

title

PTEN regulates Mdm2 expression through the P1 promoter (English)

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6 December 2017

Chun-Ju Chang

1

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6 December 2017

Daniel J Freeman

series ordinal

2

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6 December 2017

Hong Wu

series ordinal

3

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6 December 2017

language of work or name

English

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publication date

16 April 2004

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Journal of Biological Chemistry

6 December 2017

published in

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6 December 2017

volume

279

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6 December 2017

issue

28

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6 December 2017

page(s)

29841-29848

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Amplification of a gene encoding a p53-associated protein in human sarcomas

6 December 2017

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p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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The lipid phosphatase activity of PTEN is critical for its tumor supressor function

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

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21 January 2018

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Mdm2: A regulator of cell growth and death

21 January 2018

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M401488200

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6 December 2017

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