A genetic switch for epilepsy in adult mice. (Q45153533)

PubMed publication ID

15548671

10 December 2017

title

A genetic switch for epilepsy in adult mice (English)

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12 May 2020

8

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12 May 2020

Heinz Krestel

1

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12 May 2020

Derya R Shimshek

2

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12 May 2020

Thomas Nevian

4

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12 May 2020

author name string

Vidar Jensen

3

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12 May 2020

Jinhyun Kim

5

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12 May 2020

Yu Geng

6

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12 May 2020

Thomas Bast

7

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Kai Schonig

9

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Frieder Schwenk

10

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Hermann Bujard

11

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Øivind Hvalby

12

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Rolf Sprengel

13

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Peter H Seeburg

14

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language of work or name

English

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publication date

1 November 2004

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PubMed publication ID

15548671

10 December 2017

published in

Journal of Neuroscience

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volume

24

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issue

46

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page(s)

10568-10578

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Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B.

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cites work

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12 December 2020

Generation and analysis of GluR5(Q636R) kainate receptor mutant mice

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Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

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12 December 2020

Dendritic but not somatic GABAergic inhibition is decreased in experimental epilepsy.

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The role of RNA editing of kainate receptors in synaptic plasticity and seizures

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12 December 2020

Long-term, noninvasive imaging of regulated gene expression in living mice

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A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse

1 reference

12 December 2020

Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons

1 reference

12 December 2020

RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients

1 reference

12 December 2020

Disruption of CREB function in brain leads to neurodegeneration

1 reference

12 December 2020

Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus.

1 reference

12 December 2020

Stringent doxycycline dependent control of CRE recombinase in vivo

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High-efficiency transfection of individual neurons using modified electrophysiology techniques

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Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3.

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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12 December 2020

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

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12 December 2020

The other side of the engram: experience-driven changes in neuronal intrinsic excitability

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12 December 2020

Intracellular correlate of EPSP‐spike potentiation in CA1 pyramidal neurons is controlled by GABAergic modulation

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12 December 2020

AMPA receptor tetramerization is mediated by Q/R editing

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LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites

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Acquired dendritic channelopathy in temporal lobe epilepsy

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RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

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Two-photon laser scanning fluorescence microscopy

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A decrease in firing threshold observed after induction of the EPSP-spike (E-S) component of long-term potentiation in rat hippocampal slices

1 reference

12 December 2020

The human growth hormone locus: nucleotide sequence, biology, and evolution

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Long-term potentiation involves enhanced synaptic excitation relative to synaptic inhibition in guinea-pig hippocampus

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Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

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Possible mechanisms for long-lasting potentiation of synaptic transmission in hippocampal slices from guinea-pigs.

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Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice

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Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

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Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

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Patch-clamp recordings from the soma and dendrites of neurons in brain slices using infrared video microscopy

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Enhanced LTP in mice deficient in the AMPA receptor GluR2.

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Control of memory formation through regulated expression of a CaMKII transgene

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Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition.

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Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

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12 December 2020

Tissue specific control regions of the N-methyl-D-aspartate receptor subunit NR2C promoter.

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Editing status at the Q/R site of the GluR2 and GluR6 glutamate receptor subunits in the surgically excised hippocampus of patients with refractory epilepsy

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Generalized lacZ expression with the ROSA26 Cre reporter strain

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12 December 2020

10.1523/JNEUROSCI.4579-03.2004

Identifiers

DOI

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12 May 2020

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12 May 2020

PubMed publication ID

15548671

1 reference