RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response (Q47313248)

13 January 2018

title

RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response (English)

1 reference

13 January 2018

author name string

Katelyn M Green

1

1 reference

13 January 2018

M Rebecca Glineburg

2

1 reference

13 January 2018

Michael G Kearse

3

1 reference

13 January 2018

Brittany N Flores

4

1 reference

13 January 2018

Alexander E Linsalata

5

1 reference

13 January 2018

Stephen J Fedak

6

1 reference

13 January 2018

Aaron C Goldstrohm

7

1 reference

13 January 2018

Sami J Barmada

8

1 reference

13 January 2018

Peter K Todd

9

1 reference

13 January 2018

language of work or name

English

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publication date

8 December 2017

1 reference

13 January 2018

published in

Nature Communications

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13 January 2018

volume

8

1 reference

13 January 2018

issue

1

1 reference

13 January 2018

page(s)

2005

1 reference

13 January 2018

Creative Commons Attribution 4.0 International

copyright license

start time

1 December 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5722904/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS.

23 May 2018

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Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers

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23 May 2018

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23 May 2018

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Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death

23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration

23 May 2018

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C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome

23 May 2018

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23 May 2018

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Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

23 May 2018

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The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.

23 May 2018

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Leucine-tRNA initiates at CUG start codons for protein synthesis and presentation by MHC class I

23 May 2018

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The unfolded protein response: from stress pathway to homeostatic regulation

23 May 2018

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Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

23 May 2018

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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

23 May 2018

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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

23 May 2018

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Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

23 May 2018

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23 May 2018

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GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor

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23 May 2018

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Eukaryotic stress granules: the ins and outs of translation

23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

23 May 2018

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Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure

23 May 2018

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Unanticipated antigens: translation initiation at CUG with leucine

23 May 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

23 May 2018

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

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Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems

23 May 2018

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Translation initiation at non-AUG triplets in mammalian cells

23 May 2018

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Repeat-associated non-AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome

23 May 2018

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A 30-unit hexanucleotide repeat expansion in C9orf72 induces pathological lesions with dipeptide-repeat proteins and RNA foci, but not TDP-43 inclusions and clinical disease.

14 August 2018

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Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

14 August 2018

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14 August 2018

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SUnSET, a nonradioactive method to monitor protein synthesis.

14 August 2018

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14 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-02200-0

10.1038/S41467-017-02200-0

21 January 2018

Identifiers

DOI

1 reference

13 January 2018

0 references

1 reference

13 January 2018

PubMed publication ID

29222490

1 reference

13 January 2018