Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells. (Q40042686)

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scientific article published on 29 January 2016

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English	Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells.	scientific article published on 29 January 2016

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6 March 2020

Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells (English)

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6 March 2020

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6 March 2020

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Madhusudan Venkatareddy

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6 March 2020

Rakesh Verma

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Anne Kalinowski

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6 March 2020

Sanjeevkumar R Patel

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Assia Shisheva

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29 January 2016

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Journal of the American Society of Nephrology

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based on heuristic

inferred from PubMed Central ID database lookup

Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis

1 reference

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22 September 2017

PI(5)P regulates autophagosome biogenesis

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22 September 2017

Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).

1 reference

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Simultaneous high-resolution detection of multiple transcripts combined with localization of proteins in whole-mount embryos

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22 September 2017

Podocytes degrade endocytosed albumin primarily in lysosomes

1 reference

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Orchestration of cell surface proteins by Rab11.

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22 September 2017

Human podocytes perform polarized, caveolae-dependent albumin endocytosis

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22 September 2017

Autophagy in glomerular health and disease

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22 September 2017

The proximal tubule and albuminuria: really!

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22 September 2017

Dysregulated autophagy contributes to podocyte damage in Fabry's disease

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22 September 2017

Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching

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22 September 2017

Rapamycin upregulates autophagy by inhibiting the mTOR-ULK1 pathway, resulting in reduced podocyte injury

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22 September 2017

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

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22 September 2017

Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis

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22 September 2017

Endocytosis of albumin by podocytes elicits an inflammatory response and induces apoptotic cell death

1 reference

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22 September 2017

mVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking

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22 September 2017

Role of membrane traffic in the generation of epithelial cell asymmetry.

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22 September 2017

Podocyte culture: tricks of the trade

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22 September 2017

The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells

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22 September 2017

Multiple factors influence glomerular albumin permeability in rats.

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22 September 2017

Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin

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Endosome maturation

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22 September 2017

The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice

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22 September 2017

Implications of autophagy for glomerular aging and disease

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22 September 2017

Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture

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22 September 2017

Identification of the switch in early-to-late endosome transition

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22 September 2017

The emerging mechanisms of isoform-specific PI3K signalling

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22 September 2017

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

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22 September 2017

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

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22 September 2017

Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.

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22 September 2017

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes

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22 September 2017

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

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22 September 2017

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

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22 September 2017

Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity

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22 September 2017

PIKfyve: Partners, significance, debates and paradoxes

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The regulation and function of Class III PI3Ks: novel roles for Vps34.

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22 September 2017

Podocytes use FcRn to clear IgG from the glomerular basement membrane

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22 September 2017

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

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Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

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22 September 2017

The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans

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Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

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22 September 2017

Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway

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22 September 2017

A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity

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22 September 2017

Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development

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22 September 2017

PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body Morphogenesis

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22 September 2017

Active PIKfyve Associates with and Promotes the Membrane Attachment of the Late Endosome-to-trans-Golgi Network Transport Factor Rab9 Effector p40

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22 September 2017

An electron microscope study of the glomerulus in nephrosis, glomerulonephritis, and lupus erythematosus

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22 September 2017

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

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22 September 2017

PIKfyve: the road to PtdIns 5-P and PtdIns 3,5-P(2)

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22 September 2017

Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

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22 September 2017

Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes

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22 September 2017

Src family kinases are required for integrin but not PDGFR signal transduction.

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22 September 2017

Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis

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22 September 2017

Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase

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22 September 2017

Syntaxin 6 functions in trans-Golgi network vesicle trafficking

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22 September 2017

Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

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22 September 2017

Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat lgp120 (lamp-I) in MDCK cells.

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22 September 2017

Experimental membranous glomerulonephritis in rats. Quantitative studies of glomerular immune deposit formation in isolated glomeruli and whole animals

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22 September 2017

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22 September 2017

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

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22 September 2017

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

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15 June 2018

Nephrin localizes to the slit pore of the glomerular epithelial cell

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15 June 2018

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15 June 2018

Increased Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes

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15 June 2018

Characterization of plasma membrane proteins identified by monoclonal antibodies.

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15 June 2018

Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase

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20 August 2018

Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells

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20 August 2018

Two gene fragments that direct podocyte-specific expression in transgenic mice

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20 August 2018

Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies

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2 December 2018

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular interactions between albumin and proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26825532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts

1 reference

https://pubmed.ncbi.nlm.nih.gov/26825532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statin-sensitive endocytosis of albumin by glomerular podocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26825532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controversies in nephrology: response to 'renal albumin handling, facts, and artifacts'

1 reference

https://pubmed.ncbi.nlm.nih.gov/26825532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1681/ASN.2015050555

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26825532%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26825532%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26825532%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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