DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1. (Q40261691)

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scientific article published on 28 June 2006

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English	DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1.	scientific article published on 28 June 2006

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26 December 2019

DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1 (English)

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26 December 2019

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26 December 2019

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Pierre-Olivier Estève

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26 December 2019

Claude Ferec

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26 December 2019

Sriharsa Pradhan

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26 December 2019

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28 June 2006

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26 December 2019

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Journal of Biological Chemistry

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26 December 2019

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26 December 2019

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26 December 2019

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26 December 2019

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

1 reference

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

1 reference

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DNA methylation and histone modifications: teaming up to silence genes

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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CpG methylation is maintained in human cancer cells lacking DNMT1.

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

1 reference

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Mammalian DNA (cytosine-5) methyltransferases and their expression

1 reference

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Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

1 reference

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MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase

1 reference

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21 January 2018

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

1 reference

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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

1 reference

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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

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Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

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Myc represses transcription through recruitment of DNA methyltransferase corepressor

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Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

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A plausible model for the digital response of p53 to DNA damage.

1 reference

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21 January 2018

p53, the cellular gatekeeper for growth and division

1 reference

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21 January 2018

Surfing the p53 network

1 reference

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21 January 2018

The p53MH algorithm and its application in detecting p53-responsive genes

1 reference

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21 January 2018

Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.

1 reference

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21 January 2018

Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM

1 reference

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21 January 2018

Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

1 reference

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21 January 2018

Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis

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A new mathematical model for relative quantification in real-time RT-PCR

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21 January 2018

Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

1 reference

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21 January 2018

DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603724200

21 January 2018

In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression

1 reference

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21 January 2018

Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

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21 January 2018

Preferential response of cancer cells to zebularine.

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Large-scale characterization of HeLa cell nuclear phosphoproteins

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Regulation of p53 downstream genes.

1 reference

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Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding

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A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

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Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

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21 January 2018

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