Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. (Q40291997)

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scientific article published on November 2004

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English	Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.	scientific article published on November 2004

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509775%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells (English)

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Europe PubMed Central

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4 January 2020

endoplasmic reticulum

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

head and neck squamous cell carcinoma

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

Andrew M Fribley

1

1 reference

Europe PubMed Central

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4 January 2020

author name string

Qinghua Zeng

2

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4 January 2020

Cun-Yu Wang

3

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4 January 2020

language of work or name

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publication date

1 November 2004

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4 January 2020

Molecular and Cellular Biology

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4 January 2020

24

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4 January 2020

22

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4 January 2020

9695-9704

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509775%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

1 reference

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1 reference

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22 September 2017

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 reference

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

1 reference

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1 reference

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22 September 2017

Translational control in the endoplasmic reticulum stress response

1 reference

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1 reference

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Missing pieces in the NF-kappaB puzzle

1 reference

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22 September 2017

Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341

1 reference

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

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22 September 2017

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22 September 2017

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

1 reference

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22 September 2017

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

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22 September 2017

Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis

1 reference

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The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

1 reference

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22 September 2017

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

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22 September 2017

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

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22 September 2017

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

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22 September 2017

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

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1 reference

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Mitochondria and apoptosis

1 reference

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1 reference

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341.

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Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

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Head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15509775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15509775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/15509775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.24.22.9695-9704.2004

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509775%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509775%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509775%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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