Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide. (Q40341534)

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10 January 2020

title

Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide (English)

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10 January 2020

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6

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author name string

Keqiang Chen

1

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Pablo Iribarren

2

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Jinyue Hu

3

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Jianhong Chen

4

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Wanghua Gong

5

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Stephen Lockett

7

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Nancy M Dunlop

8

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Ji Ming Wang

9

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language of work or name

English

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publication date

9 December 2005

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Journal of Biological Chemistry

10 January 2020

published in

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volume

281

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issue

6

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page(s)

3651-3659

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Structure and function of amyloid in Alzheimer's disease

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Inflammation and Alzheimer's disease: relationships between pathogenic mechanisms and clinical expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglia cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plague degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglia and the immune pathology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Up-regulation of FPR2, a chemotactic receptor for amyloid beta 1-42 (A beta 42), in murine microglial cells by TNF alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Formyl-peptide receptors revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Role of microglia in central nervous system infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Immunotherapeutic Approaches to Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

IL-4 Down-Regulates Lipopolysaccharide-Induced Formyl Peptide Receptor 2 in Murine Microglial Cells by Inhibiting the Activation of Mitogen-Activated Protein Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglia and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Broad expression of Toll-like receptors in the human central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Toll-like receptor 2 modulates the proinflammatory milieu in Staphylococcus aureus-induced brain abscess

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Endogenous ligands of Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Alarmins: chemotactic activators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508125200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508125200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16339765%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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