Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts (Q40521650)

21 September 2017

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts (English)

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21 September 2017

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21 September 2017

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21 September 2017

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Eric Karsenti

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21 September 2017

Rainer Pepperkok

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Stéphane Brunet

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Stéphane Brunet

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1

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author name string

Teresa Sardon

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2

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21 September 2017

Timo Zimmerman

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21 September 2017

language of work or name

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22 September 2004

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Molecular Biology of the Cell

21 September 2017

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21 September 2017

15

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21 September 2017

12

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21 September 2017

5318-5328

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Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

21 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Importin alpha-regulated nucleation of microtubules by TPX2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Human TPX2 is required for targeting Aurora-A kinase to the spindle

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

The Ran GTPase: theme and variations

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

The mitotic spindle: a self-made machine

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Running on Ran: nuclear transport and the mitotic spindle.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

TPX2, A novel xenopus MAP involved in spindle pole organization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Photoactivation turns green fluorescent protein red.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Isolation of a protein that is essential for the first step of nuclear protein import

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Preparation of modified tubulins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Mitotic spindle assembly by two different pathways in vitro

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Cell cycle. Some importin news about spindle assembly

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Spindles get the ran around

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=532013

Photoactivation of green fluorescent protein

20 August 2018

1 reference

12 December 2020

Studying the composition and function of centrosomes in vertebrates

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12 December 2020

Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes

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12 December 2020

The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5

1 reference

12 December 2020

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

12 December 2020

A novel mechanism for activation of the protein kinase Aurora A

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12 December 2020

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E04-05-0385

1 reference

21 September 2017

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21 September 2017

PubMed publication ID

15385625

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