Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. (Q41423732)

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scientific article published on December 1994

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English	Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.	scientific article published on December 1994

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24 October 2019

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells (English)

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24 October 2019

Alzheimer's disease

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phosphorylation

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Diane P. Hanger

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24 October 2019

Simon Lovestone

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24 October 2019

Jean-Marc Gallo

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24 October 2019

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C H Reynolds

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24 October 2019

D Latimer

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24 October 2019

D R Davis

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24 October 2019

B H Anderton

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24 October 2019

S Mulot

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24 October 2019

B Marquardt

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24 October 2019

S Stabel

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24 October 2019

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1 December 1994

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24 October 2019

Current Biology

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24 October 2019

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24 October 2019

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24 October 2019

1077-1086

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24 October 2019

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

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Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

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beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

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Spongiform alterations in brain biopsies of presenile dementia

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Alzheimer's disease: paired helical filaments and cytomembranes

1 reference

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Fetal-type phosphorylation of the tau in paired helical filaments

1 reference

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7 January 2021

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

1 reference

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Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease.

1 reference

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The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

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7 January 2021

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Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

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p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

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Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

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based on heuristic

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PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta.

1 reference

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7 January 2021

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Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

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Signal transduction via the MAP kinases: proceed at your own RSK.

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The pathway to signal achievement

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Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells

1 reference

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7 January 2021

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Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

1 reference

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7 January 2021

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Phosphorylation of tau protein in tau-transfected 3T3 cells

1 reference

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7 January 2021

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Overexpression of tau protein in COS-1 cells results in the stabilization of centrosome-independent microtubules and extension of cytoplasmic processes

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7 January 2021

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

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Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus

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About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation.

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Neuritic pathology and dementia in Alzheimer's disease

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Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.

1 reference

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On target with a new mechanism for the regulation of protein phosphorylation

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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Neurofilament Monoclonal Antibodies RT97 and 8D8 Recognize Different Modified Epitopes in Paired Helical Filament‐τ in Alzheimer's Disease

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27 Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3t3-L1 fibroblasts

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Identifiers

10.1016/S0960-9822(00)00246-3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7704571%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7704571%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

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