Prion-Like Propagation of Post-Translationally Modified Tau in Alzheimer's Disease: A Hypothesis (Q89459556)

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5 April 2020

title

Prion-Like Propagation of Post-Translationally Modified Tau in Alzheimer's Disease: A Hypothesis (English)

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5 April 2020

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Subashchandrabose Chinnathambi

series ordinal

2

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5 April 2020

author name string

Shweta Kishor Sonawane

series ordinal

1

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publication date

7 July 2018

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Journal of Molecular Neuroscience

5 April 2020

published in

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volume

65

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issue

4

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5 April 2020

page(s)

480-490

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A protein factor essential for microtubule assembly

5 April 2020

cites work

1 reference

12 December 2020

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

12 December 2020

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

1 reference

12 December 2020

Neuropathological stageing of Alzheimer-related changes

1 reference

12 December 2020

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

12 December 2020

Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells

1 reference

12 December 2020

Scrapie PrP 27-30 is a sialoglycoprotein

1 reference

12 December 2020

The distribution of tau in the mammalian central nervous system

1 reference

12 December 2020

Tau protein from Alzheimer's disease patients is glycated at its tubulin-binding domain.

1 reference

12 December 2020

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

1 reference

12 December 2020

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

1 reference

12 December 2020

Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure

1 reference

12 December 2020

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

1 reference

12 December 2020

Analysis of microtubule-associated protein tau glycation in paired helical filaments.

1 reference

12 December 2020

The anti-prion activity of Congo red. Putative mechanism

1 reference

12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

12 December 2020

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

1 reference

12 December 2020

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

1 reference

12 December 2020

An immunochemical study on tau glycation in paired helical filaments

1 reference

12 December 2020

Phosphorylated tau can promote tubulin assembly

1 reference

12 December 2020

Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease

1 reference

12 December 2020

Cd36, a member of the class b scavenger receptor family, as a receptor for advanced glycation end products

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

12 December 2020

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

1 reference

12 December 2020

The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein

1 reference

12 December 2020

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

1 reference

12 December 2020

Tau gene mutations: dissecting the pathogenesis of FTDP-17.

1 reference

12 December 2020

A novel generation of heparan sulfate mimetics for the treatment of prion diseases.

1 reference

12 December 2020

Nonenzymatic glycation at the N terminus of pathogenic prion protein in transmissible spongiform encephalopathies

1 reference

12 December 2020

Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro

1 reference

12 December 2020

Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain

1 reference

12 December 2020

Post-translational modifications of tau protein in Alzheimer's disease

1 reference

12 December 2020

Tau phosphorylation in neuronal cell function and dysfunction

1 reference

12 December 2020

Regulation of tau isoform expression and dementia

1 reference

12 December 2020

Molecular pathogenesis of Parkinson disease

1 reference

12 December 2020

Prions and exosomes: from PrPc trafficking to PrPsc propagation

1 reference

12 December 2020

Site-specific nitration differentially influences tau assembly in vitro

1 reference

12 December 2020

Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity

1 reference

12 December 2020

The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

1 reference

12 December 2020

The "jaws" of the tau-microtubule interaction.

1 reference

12 December 2020

Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

1 reference

12 December 2020

Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage

1 reference

12 December 2020

Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro

1 reference

12 December 2020

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

1 reference

12 December 2020

FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action.

1 reference

12 December 2020

Development of tau aggregation inhibitors for Alzheimer's disease

1 reference

12 December 2020

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

1 reference

12 December 2020

Propagation of tau misfolding from the outside to the inside of a cell.

1 reference

12 December 2020

Doxorubicin and congo red effectiveness on prion infectivity in golden Syrian hamster

1 reference

12 December 2020

Autophagy, prion infection and their mutual interactions

1 reference

12 December 2020

Glycosylation of PrPC determines timing of neuroinvasion and targeting in the brain following transmissible spongiform encephalopathy infection by a peripheral route

1 reference

12 December 2020

'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy

1 reference

12 December 2020

Immunotherapy for prion diseases: opportunities and obstacles

1 reference

12 December 2020

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

1 reference

12 December 2020

Phosphorylation of Tau at Thr212, Thr231, and Ser262 Combined Causes Neurodegeneration

1 reference

12 December 2020

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

1 reference

12 December 2020

Development of monoclonal antibodies specific for glycated prion protein.

1 reference

12 December 2020

Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding

1 reference

12 December 2020

Trans-cellular propagation of Tau aggregation by fibrillar species

1 reference

12 December 2020

Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates

1 reference

12 December 2020

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

1 reference

12 December 2020

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

1 reference

12 December 2020

Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

1 reference

12 December 2020

Immunotherapy in prion disease

1 reference

12 December 2020

Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties

1 reference

12 December 2020

Physiological release of endogenous tau is stimulated by neuronal activity.

1 reference

12 December 2020

A double-blind, placebo-controlled, ascending-dose, randomized study to evaluate the safety, tolerability and effects on cognition of AL-108 after 12 weeks of intranasal administration in subjects with mild cognitive impairment

1 reference

12 December 2020

Mechanisms of protein seeding in neurodegenerative diseases

1 reference

12 December 2020

Exosome release from infected dendritic cells: a clue for a fast spread of prions in the periphery?

1 reference

12 December 2020

Antibody uptake into neurons occurs primarily via clathrin-dependent Fcγ receptor endocytosis and is a prerequisite for acute tau protein clearance.

1 reference

12 December 2020

Parkinson's disease: a review

1 reference

12 December 2020

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

1 reference

12 December 2020

Role of advanced glycation end products in cellular signaling

1 reference

12 December 2020

Distinct tau prion strains propagate in cells and mice and define different tauopathies

1 reference

12 December 2020

The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

1 reference

12 December 2020

Proteopathic tau seeding predicts tauopathy in vivo.

1 reference

12 December 2020

Investigation of phosphoproteome in RAGE signaling

1 reference

12 December 2020

Invited review: Prion-like transmission and spreading of tau pathology

1 reference

12 December 2020

A phase II trial of tideglusib in Alzheimer's disease

1 reference

12 December 2020

Tau immunization: a cautionary tale?

1 reference

12 December 2020

Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology

1 reference

12 December 2020

Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation.

1 reference

12 December 2020

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

1 reference

12 December 2020

Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII.

1 reference

12 December 2020

Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake

1 reference

12 December 2020

Role of RAGE in Alzheimer's Disease

1 reference

12 December 2020

NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein

1 reference

12 December 2020

Glyceraldehyde caused Alzheimer's disease-like alterations in diagnostic marker levels in SH-SY5Y human neuroblastoma cells

1 reference

12 December 2020

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

1 reference

12 December 2020

Tau in physiology and pathology

1 reference

12 December 2020

Glycation alter the process of Tau phosphorylation to change Tau isoforms aggregation property

1 reference

12 December 2020

How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability?

1 reference

12 December 2020

PrPSc-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains

1 reference

12 December 2020

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain

1 reference

12 December 2020

Neuronal activity enhances tau propagation and tau pathology in vivo.

1 reference

12 December 2020

1 reference

12 December 2020

Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration.

1 reference

12 December 2020

Formation, release, and internalization of stable tau oligomers in cells

1 reference

12 December 2020

Loss of Bin1 Promotes the Propagation of Tau Pathology

1 reference

12 December 2020

Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders

1 reference

12 December 2020

The Prion-Like Behavior of Assembled Tau in Transgenic Mice

1 reference

12 December 2020

Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo.

1 reference

12 December 2020

Characterization of TauC3 antibody and demonstration of its potential to block tau propagation

1 reference

12 December 2020

Propagation of Tau Aggregates and Neurodegeneration

1 reference

12 December 2020

10.1007/S12031-018-1111-5

Identifiers

DOI

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5 April 2020

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