DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis (Q89900986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32103174%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis (English)

1 reference

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Protein kinase, DNA-activated, catalytic subunit

9 April 2020

main subject

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X-ray repair cross complementing 5

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U3 snoRNA binding

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Protein kinase, DNA activated, catalytic polypeptide

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X-ray repair complementing defective repair in Chinese hamster cells 6

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1 reference

12

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9 April 2020

9

Carolyn R Bertozzi

1 reference

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9 April 2020

13

Shan Zha

1 reference

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9 April 2020

author name string

Zhengping Shao

1

1 reference

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9 April 2020

Ryan A Flynn

2

1 reference

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9 April 2020

Jennifer L Crowe

3

1 reference

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9 April 2020

Yimeng Zhu

4

1 reference

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9 April 2020

Jialiang Liang

5

1 reference

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9 April 2020

Wenxia Jiang

6

1 reference

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9 April 2020

Fardin Aryan

7

1 reference

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9 April 2020

Patrick Aoude

8

1 reference

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9 April 2020

Verna M Estes

10

1 reference

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9 April 2020

Brian J Lee

11

1 reference

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9 April 2020

Eliezer Calo

14

1 reference

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9 April 2020

language of work or name

English

0 references

publication date

26 February 2020

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9 April 2020

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9 April 2020

volume

579

1 reference

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9 April 2020

issue

7798

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9 April 2020

page(s)

291-296

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

9 April 2020

cites work

1 reference

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7 January 2021

Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining

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7 January 2021

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

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7 January 2021

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

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7 January 2021

Mechanisms of programmed DNA lesions and genomic instability in the immune system.

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7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

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7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

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7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

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7 January 2021

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

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7 January 2021

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

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7 January 2021

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

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7 January 2021

Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination

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7 January 2021

Tumor spectrum analysis in p53-mutant mice

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7 January 2021

DNA-PK: the means to justify the ends?

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7 January 2021

DNA-PK: a dynamic enzyme in a versatile DSB repair pathway

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7 January 2021

Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination

1 reference

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7 January 2021

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

1 reference

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7 January 2021

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination

1 reference

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7 January 2021

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

1 reference

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7 January 2021

Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence

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7 January 2021

Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection

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7 January 2021

Characterization of the RNA binding properties of Ku protein

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7 January 2021

Structural Insights into Yeast Telomerase Recruitment to Telomeres.

1 reference

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7 January 2021

Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model

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7 January 2021

A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

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7 January 2021

Ribosomopathies: human disorders of ribosome dysfunction

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7 January 2021

Haematopoietic stem cells require a highly regulated protein synthesis rate

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7 January 2021

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis.

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7 January 2021

p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells

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7 January 2021

Attempt at preclinical identification of Huntington's disease using the WAIS.

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7 January 2021

Systematic discovery of Xist RNA binding proteins

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7 January 2021

Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit.

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7 January 2021

Online Nanoflow RP−RP-MS Reveals Dynamics of Multicomponent Ku Complex in Response to DNA Damage

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7 January 2021

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits

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7 January 2021

irCLIP platform for efficient characterization of protein-RNA interactions

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7 January 2021

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2041-2

7 January 2021

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

1 reference

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7 January 2021

Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2041-2

7 January 2021

The role of DNA dependent protein kinase in synapsis of DNA ends.

1 reference

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7 January 2021

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage.

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7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

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7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency

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7 January 2021

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice

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7 January 2021

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination

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7 January 2021

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

1 reference

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7 January 2021

Reduced expression of the mouse ribosomal protein Rpl17 alters the diversity of mature ribosomes by enhancing production of shortened 5.8S rRNA.

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7 January 2021

5'-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decay

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7 January 2021

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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7 January 2021

Cytoscape: a software environment for integrated models of biomolecular interaction networks

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7 January 2021

Mfold web server for nucleic acid folding and hybridization prediction

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7 January 2021

VARNA: Interactive drawing and editing of the RNA secondary structure

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7 January 2021

The clinical features and diagnosis of glomus tumours (author's transl)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/32103174

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41586-020-2041-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32103174%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference