Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding (Q90212270)

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scientific article published on 07 June 2018

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English	Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding	scientific article published on 07 June 2018

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

title

Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding (English)

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Europe PubMed Central

PMC publication ID

6698812

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12 April 2020

author

Samuel Ken-En Gan

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4

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

author name string

Chinh Tran-To Su

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1

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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Wai-Heng Lua

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2

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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Wei-Li Ling

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3

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

publication date

7 June 2018

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

published in

Antibodies (Basel)

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

volume

7

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6698812

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12 April 2020

issue

2

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Europe PubMed Central

PMC publication ID

6698812

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

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12 April 2020

copyright license

Creative Commons Attribution 4.0 International

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7 June 2018

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Continuous cultures of fused cells secreting antibody of predefined specificity

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PubMed

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FcalphaRI (CD89) as a novel trigger molecule for bispecific antibody therapy

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Molecular dynamics and free-energy calculations applied to affinity maturation in antibody 48G7.

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Structural and functional properties of membrane and secreted IgD.

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PubMed

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Evidence of allosteric conformational changes in the antibody constant region upon antigen binding

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PubMed

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12 December 2020

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IgA function--variations on a theme

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PubMed

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Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics

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Solution structure of human secretory component and implications for biological function

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Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy

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Fast procedure for reconstruction of full-atom protein models from reduced representations.

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Paul Ehrlich's magic bullet concept: 100 years of progress

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Improved prediction of protein side-chain conformations with SCWRL4

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How antibodies fold

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Structure and function of immunoglobulins

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Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization.

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The function and regulation of immunoglobulin D.

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Immunoglobulin A: A next generation of therapeutic antibodies?

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Three-dimensional structures of membrane proteins from genomic sequencing

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IgGA: a "cross-isotype" engineered human Fc antibody domain that displays both IgG-like and IgA-like effector functions.

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Rigidity Emerges during Antibody Evolution in Three Distinct Antibody Systems: Evidence from QSFR Analysis of Fab Fragments

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IgA as therapeutic antibody

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Ig Constant Region Effects on Variable Region Structure and Function

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Identifiers

DOI

10.3390/ANTIB7020020

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stated in

Europe PubMed Central

PMC publication ID

6698812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

PMC publication ID

6698812

1 reference

stated in

Europe PubMed Central

PMC publication ID

6698812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

PubMed publication ID

31544872

1 reference

stated in

Europe PubMed Central

PMC publication ID

6698812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31544872%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

 

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