Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis (Q24563189)

6

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author name string

Andrea Ballabeni

1

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Marina Melixetian

2

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Raffaella Zamponi

3

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Laura Masiero

4

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Federica Marinoni

Loss of Geminin induces rereplication in the presence of functional p53

5

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language of work or name

English

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publication date

4 August 2004

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published in

The EMBO Journal

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volume

23

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issue

15

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page(s)

3122-32

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cites work

1 reference

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Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

24 March 2017

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Direct interaction of geminin and Six3 in eye development

24 March 2017

1 reference

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Making sense of eukaryotic DNA replication origins

24 March 2017

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Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle

24 March 2017

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Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle

24 March 2017

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

24 March 2017

1 reference

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Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1

24 March 2017

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Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

24 March 2017

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

24 March 2017

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

24 March 2017

1 reference

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Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC

24 March 2017

1 reference

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Predicting coiled coils from protein sequences

24 March 2017

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Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

24 March 2017

1 reference

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Cdc7 is required throughout the yeast S phase to activate replication origins.

24 March 2017

1 reference

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Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

24 March 2017

1 reference

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An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

24 March 2017

1 reference

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Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation

24 March 2017

1 reference

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The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

24 March 2017

1 reference

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Cyclin-dependent kinases and S phase control in mammalian cells

24 March 2017

1 reference

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The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

24 March 2017

1 reference

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Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity

24 March 2017

1 reference

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The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

24 March 2017

1 reference

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Initiating DNA synthesis: from recruiting to activating the MCM complex

24 March 2017

1 reference

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The Cdt1 protein is required to license DNA for replication in fission yeast

24 March 2017

1 reference

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XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

24 March 2017

1 reference

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Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation

24 March 2017

1 reference

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Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex

10 May 2017

1 reference

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Replication origins: why do we need so many?

27 September 2017

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The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication

27 September 2017

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Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins

27 September 2017

1 reference

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Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Control of DNA replication and chromosome ploidy by geminin and cyclin A

27 September 2017

1 reference

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Mammalian nuclei become licensed for DNA replication during late telophase

27 September 2017

1 reference

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Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins.

27 September 2017

1 reference

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MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

DNA replication licensing and human cell proliferation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Stepwise assembly of initiation proteins at budding yeast replication origins in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Cell cycle-regulated proteolysis of mitotic target proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

The Cdc7 protein kinase is required for origin firing during S phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Stepwise assembly of initiation complexes at budding yeast replication origins during the cell cycle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed mammalian cells

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600314

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600314

Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514931

CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15257290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7600314

1 reference

1 reference

1 reference

PubMed publication ID

15257290

1 reference