Serine is a natural ligand and allosteric activator of pyruvate kinase M2 (Q27674495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Serine is a natural ligand and allosteric activator of pyruvate kinase M2 (English)

1 reference

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Erratum: Corrigendum: Serine is a natural ligand and allosteric activator of pyruvate kinase M2

10 March 2020

corrigendum / erratum

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author

Petra Hillmann

2

1 reference

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10 March 2020

Oliver D K Maddocks

5

1 reference

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10 March 2020

Christian Frezza

11

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10 March 2020

Eyal Gottlieb

13

1 reference

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10 March 2020

10

Karen H Vousden

1 reference

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10 March 2020

author name string

Barbara Chaneton

1

1 reference

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10 March 2020

Liang Zheng

3

1 reference

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10 March 2020

Agnès C L Martin

4

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10 March 2020

Achuthanunni Chokkathukalam

6

1 reference

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10 March 2020

Joseph E Coyle

7

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10 March 2020

Andris Jankevics

8

1 reference

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10 March 2020

Finn P Holding

9

1 reference

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10 March 2020

Marc O'Reilly

12

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10 March 2020

language of work or name

English

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publication date

14 October 2012

1 reference

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10 March 2020

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10 March 2020

volume

491

1 reference

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10 March 2020

issue

7424

1 reference

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10 March 2020

page(s)

458-462

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

10 March 2020

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1 reference

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20 March 2017

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Pyruvate kinase type M2 and its role in tumor growth and spreading

20 March 2017

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

20 March 2017

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Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

7 April 2017

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Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

29 September 2017

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

29 September 2017

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

29 September 2017

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

29 September 2017

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29 September 2017

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29 September 2017

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Evidence for an alternative glycolytic pathway in rapidly proliferating cells

29 September 2017

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Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

29 September 2017

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Targeting metabolic transformation for cancer therapy.

29 September 2017

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Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

29 September 2017

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

29 September 2017

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A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity

29 September 2017

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29 September 2017

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29 September 2017

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L-serine in disease and development

29 September 2017

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The allosteric regulation of pyruvate kinase

29 September 2017

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In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate

29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

2 June 2018

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21 January 2018

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Structural and kinetic differences between the M2 type pyruvate kinases from lung and various tumors

21 January 2018

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Nitrogen metabolism in tumor bearing mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064226

12 December 2020

inferred from PubMed ID database lookup

Correction of 13C mass isotopomer distributions for natural stable isotope abundance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064226

12 December 2020

inferred from PubMed ID database lookup

On the use of the merging R factor as a quality indicator for X-ray data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

7 January 2021

inferred from DOI database lookup

Global indicators of X-ray data quality

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11540

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1000007436

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23064226

2 references