Retinol Dehydrogenases Regulate Vitamin A Metabolism for Visual Function (Q28077029)

Akiko Maeda

series ordinal

2

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language of work or name

1 reference

22 November 2016

9 references

25 April 2019

22 June 2019

12 September 2019

28 September 2019

11 October 2019

12 October 2019

7 November 2019

16 October 2020

9 references

25 April 2019

22 June 2019

12 September 2019

28 September 2019

11 October 2019

12 October 2019

7 November 2019

16 October 2020

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issue

11

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Creative Commons Attribution

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8 references

25 April 2019

22 June 2019

12 September 2019

28 September 2019

11 October 2019

12 October 2019

7 November 2019

16 October 2020

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ScienceSource

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cites work

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Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity

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Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

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Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE

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Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina

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Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol

20 March 2017

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Activity of human 11-cis-retinol dehydrogenase (Rdh5) with steroids and retinoids and expression of its mRNA in extra-ocular human tissue

20 March 2017

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Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal

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Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus

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Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases

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11-cis retinol dehydrogenase mutations as a major cause of the congenital night-blindness disorder known as fundus albipunctatus

20 March 2017

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Chemistry of the retinoid (visual) cycle

20 March 2017

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Characterization of a dehydrogenase activity responsible for oxidation of 11-cis-retinol in the retinal pigment epithelium of mice with a disrupted RDH5 gene. A model for the human hereditary disease fundus albipunctatus

20 March 2017

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The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases

20 March 2017

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Retinol dehydrogenase 13 protects the mouse retina from acute light damage

20 March 2017

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RDH13L, an enzyme responsible for the aldehyde-alcohol redox coupling reaction (AL-OL coupling reaction) to supply 11-cis retinal in the carp cone retinoid cycle

20 March 2017

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The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development

20 March 2017

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Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina

20 March 2017

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RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development

20 March 2017

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Functional characterization of mouse RDH11 as a retinol dehydrogenase involved in dark adaptation in vivo

20 March 2017

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Prostate short-chain dehydrogenase reductase 1 (PSDR1): a new member of the short-chain steroid dehydrogenase/reductase family highly expressed in normal and neoplastic prostate epithelium

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Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

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7 April 2017

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Short-chain dehydrogenases/reductases (SDR)

7 April 2017

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Acute Stress Responses Are Early Molecular Events of Retinal Degeneration in Abca4-/-Rdh8-/- Mice After Light Exposure

7 April 2017

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Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium

29 September 2017

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Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice

29 September 2017

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29 September 2017

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29 September 2017

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Molecular pharmacodynamics of emixustat in protection against retinal degeneration

29 September 2017

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Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships

29 September 2017

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Retinol dehydrogenases: membrane-bound enzymes for the visual function

29 September 2017

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New syndrome with retinitis pigmentosa is caused by nonsense mutations in retinol dehydrogenase RDH11.

29 September 2017

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The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis

29 September 2017

1 reference

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Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina

29 September 2017

1 reference

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PLXNC1 and RDH13 associated with bilateral convergent strabismus with exophthalmus in German Brown cattle

29 September 2017

1 reference

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A2E accumulation influences retinal microglial activation and complement regulation

29 September 2017

1 reference

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Fundus albipunctatus: novel mutations and phenotypic description of Israeli patients.

29 September 2017

1 reference

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Vitamin A metabolism in rod and cone visual cycles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Gene therapy for Leber congenital amaurosis: advances and future directions.

29 September 2017

1 reference

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Primary amines protect against retinal degeneration in mouse models of retinopathies

29 September 2017

1 reference

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Aromatic lipophilic spin traps effectively inhibit RPE65 isomerohydrolase activity

29 September 2017

1 reference

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p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation

29 September 2017

1 reference

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Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.

29 September 2017

1 reference

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Key enzymes of the retinoid (visual) cycle in vertebrate retina

29 September 2017

1 reference

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Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.

29 September 2017

1 reference

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CAROTENOIDS AND THE VISUAL CYCLE

29 September 2017

1 reference

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Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells

29 September 2017

1 reference

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Phospholipid meets all-trans-retinal: the making of RPE bisretinoids

29 September 2017

1 reference

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Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Redundant and unique roles of retinol dehydrogenases in the mouse retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

A novel cone visual cycle in the cone-dominated retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.

29 September 2017

1 reference

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Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration

29 September 2017

1 reference

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Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Properties of short-chain dehydrogenase/reductase RalR1: characterization of purified enzyme, its orientation in the microsomal membrane, and distribution in human tissues and cell lines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Structure and function of retinol dehydrogenases of the short chain dehydrogenase/reductase family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

TAUTOMERIC FORMS OF METARHODOPSIN.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Intracellular localization and membrane topology of 11-cis retinol dehydrogenase in the retinal pigment epithelium suggest a compartmentalized synthesis of 11-cis retinaldehyde.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

29 September 2017

1 reference

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Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus.

29 September 2017

1 reference

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Classification and nomenclature of the superfamily of short-chain dehydrogenases/reductases (SDRs).

29 September 2017

1 reference

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ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

2 June 2018

1 reference

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Phenotypic variability in RDH5 retinopathy (Fundus Albipunctatus).

2 June 2018

1 reference

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The Molecular Basis of Visual Excitation

2 June 2018

1 reference

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Muller cells of chicken retina synthesize 11-cis-retinol

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Local vibrational coherences drive the primary photochemistry of vision

2 June 2018

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The N-terminus of retinol dehydrogenase type 1 signals cytosolic orientation in the microsomal membrane

21 January 2018

1 reference

Elements in the N-terminal signaling sequence that determine cytosolic topology of short-chain dehydrogenases/reductases. Studies with retinol dehydrogenase type 1 and cis-retinol/androgen dehydrogenase type 1.

21 January 2018

1 reference

Cone and rod dysfunction in fundus albipunctatus with RDH5 mutation: an electrophysiological study

21 January 2018

1 reference

A novel Gly35Ser mutation in the RDH5 gene in a Japanese family with fundus albipunctatus associated with cone dystrophy

21 January 2018

1 reference

Leber congenital amaurosis

21 January 2018

1 reference

Treatment of a retinal dystrophy, fundus albipunctatus, with oral 9-cis-{beta}-carotene

21 January 2018

1 reference

Leber congenital amaurosis: retinol dehydrogenases are the culprit

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133129

Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction

27 November 2018

1 reference

12 December 2020

A frequent 1085delC/insGAAG mutation in the RDH5 gene in Japanese patients with fundus albipunctatus

1 reference

12 December 2020

EPR spin trapping detection of carbon-centered carotenoid and beta-ionone radicals

1 reference

12 December 2020

Late-onset CORD in a patient with RDH12 mutations identified by whole exome sequencing

1 reference

12 December 2020

Detection of some retinoid radicals using high-performance liquid chromatography with electron spin resonance spectroscopy or electrochemical detection

1 reference

12 December 2020

Evaluation of genes identified by microarray analysis in favorable neuroblastoma

1 reference

12 December 2020

Identifiers

0 references

1 reference

PubMed publication ID

27879662

1 reference