Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53 (Q28198423)

1

0 references

T Maeda

2

0 references

T Aso

3

0 references

T Ito

4

0 references

T Kondo

5

0 references

K Koike

6

0 references

M Hatakeyama

Journal of Biological Chemistry

7

0 references

language of work or name

English

0 references

publication date

11 June 1999

0 references

published in

0 references

volume

274

0 references

issue

24

0 references

page(s)

17003-10

0 references

cites work

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

An RNA polymerase II elongation factor encoded by the human ELL gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 functions as a cell cycle control protein in osteosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Presence of a potent transcription activating sequence in the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Wild-type p53 can down-modulate the activity of various promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Wild-type p53 binds to the TATA-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Highly controlled heterologous gene expression through combined utilization of the tetracycline-repressible transactivator and the lac repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Control of retinoblastoma protein-independent hematopoietic cell cycle by the pRB-related p130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Developmental analysis and subcellular localization of the murine homologue of ELL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Refined solution structure of the oligomerization domain of the tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Solution structure of the tetrameric minimum transforming domain of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

p53 domains: identification and characterization of two autonomous DNA-binding regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Mapping of the p53 and mdm-2 Interaction Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Overexpression of the MEN/ELL protein, an RNA polymerase II elongation factor, results in transformation of Rat1 cells with dependence on the lysine-rich region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.24.17003

21 January 2018

Identifiers

DOI

10.1074/JBC.274.24.17003

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10358050

1 reference

Consolidated OpenCitations Corpus – April 2017