Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes (Q28506980)

24 January 2017

title

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes (English)

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Transformation related protein 53

24 January 2017

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GOA release 2020-03-11

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RB transcriptional corepressor 1

GOA release 2020-03-11

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GOA release 2020-03-11

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M. L. Bajenaru

1

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24 January 2017

J. Donahoe

2

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24 January 2017

T. Corral

3

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24 January 2017

K. M. Reilly

4

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24 January 2017

S. Brophy

5

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24 January 2017

A. Pellicer

6

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24 January 2017

D. H. Gutmann

7

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24 January 2017

publication date

15 March 2001

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24 January 2017

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24 January 2017

volume

33

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24 January 2017

issue

4

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24 January 2017

page(s)

314–323

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

24 January 2017

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

21 January 2018

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21 January 2018

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Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

21 January 2018

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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

21 January 2018

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Mouse models of tumor development in neurofibromatosis type 1

21 January 2018

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

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Proliferation of human malignant astrocytomas is dependent on Ras activation

21 January 2018

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Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

21 January 2018

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Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

21 January 2018

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Precocious puberty in children with neurofibromatosis type 1.

21 January 2018

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Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

21 January 2018

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Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

21 January 2018

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Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo

21 January 2018

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Effects of an Rb mutation in the mouse

21 January 2018

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Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

21 January 2018

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Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

21 January 2018

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Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

21 January 2018

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Natural history of optic pathway tumors in children with neurofibromatosis type 1: a longitudinal study.

21 January 2018

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21 January 2018

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NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity

21 January 2018

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21 January 2018

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Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

21 January 2018

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Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

21 January 2018

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The management of brainstem gliomas in patients with neurofibromatosis 1.

21 January 2018

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Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

21 January 2018

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Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

21 January 2018

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

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Mouse tumor model for neurofibromatosis type 1

21 January 2018

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The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

21 January 2018

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Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

21 January 2018

1 reference

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10.1002/1098-1136(20010315)33:4<314::AID-GLIA1030>3.0.CO;2-Q

21 January 2018

Identifiers

DOI

0 references

1 reference