Arhgap36-dependent activation of Gli transcription factors (Q34002623)

25024229

30 July 2017

title

Arhgap36-dependent activation of Gli transcription factors (English)

1 reference

30 July 2017

1

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12 June 2020

Volker Hovestadt

6

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12 June 2020

David T. W. Jones

8

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12 June 2020

Ari J Firestone

10

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12 June 2020

Stefan M. Pfister

11

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12 June 2020

James K. Chen

13

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12 June 2020

7

Marcel Kool

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12 June 2020

3

Alexander Y Payumo

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12 June 2020

author name string

Jun Ni

2

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12 June 2020

Vien Nguyen

4

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12 June 2020

J Aaron Crapster

5

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12 June 2020

John K Mich

9

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12 June 2020

Yoon-Jae Cho

12

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12 June 2020

language of work or name

English

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publication date

14 July 2014

1 reference

25024229

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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volume

111

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issue

30

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12 June 2020

page(s)

11061-11066

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Novel mutations target distinct subgroups of medulloblastoma.

12 June 2020

cites work

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5 July 2018

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Hedgehog signaling controls homeostasis of adult intestinal smooth muscle

5 July 2018

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5 July 2018

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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

5 July 2018

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A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

5 July 2018

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Medulloblastoma comprises four distinct molecular variants

5 July 2018

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Mechanism and evolution of cytosolic Hedgehog signal transduction

5 July 2018

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Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

5 July 2018

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

5 July 2018

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Hedgehog beyond medulloblastoma and basal cell carcinoma

5 July 2018

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Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

5 July 2018

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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

5 July 2018

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Dual and opposing roles of primary cilia in medulloblastoma development

5 July 2018

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Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

5 July 2018

1 reference

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Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

5 July 2018

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The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling

5 July 2018

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Dissecting the thermodynamics of GAP-RhoA interactions

5 July 2018

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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

5 July 2018

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Intraflagellar transport: from molecular characterisation to mechanism

5 July 2018

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Patched1 regulates hedgehog signaling at the primary cilium

5 July 2018

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Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

5 July 2018

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

5 July 2018

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Vertebrate Smoothened functions at the primary cilium

5 July 2018

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Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

5 July 2018

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5 July 2018

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Rho GTPase-activating proteins in cell regulation

5 July 2018

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

5 July 2018

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Small molecule modulation of Smoothened activity

5 July 2018

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Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

5 July 2018

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5 July 2018

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

5 July 2018

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

5 July 2018

1 reference

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Sonic hedgehog regulates the growth and patterning of the cerebellum

5 July 2018

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Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

5 July 2018

1 reference

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Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121843

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

5 July 2018

1 reference

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Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

5 July 2018

1 reference

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Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

5 July 2018

1 reference

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Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121843

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121843

Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121843

Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

5 July 2018

1 reference

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Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.

21 January 2018

1 reference

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Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

21 January 2018

1 reference

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Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1073/PNAS.1322362111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25024229%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

0 references

1 reference

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12 June 2020

25024229

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