How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation (Q35700328)

9 August 2017

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title

How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation (English)

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9 August 2017

author name string

Józefa Wsierska-Gadek

series ordinal

1

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9 August 2017

Marcel Horky

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

1 December 2003

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Annals of the New York Academy of Sciences

9 August 2017

published in

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9 August 2017

volume

1010

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9 August 2017

page(s)

266-272

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Multiple roles of the tumor suppressor p53.

9 August 2017

cites work

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

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Mdm2 promotes the rapid degradation of p53

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Regulation of p53 stability by Mdm2

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Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

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Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

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JNK targets p53 ubiquitination and degradation in nonstressed cells

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MEKK1/JNK signaling stabilizes and activates p53.

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Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

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Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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21 January 2018

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21 January 2018

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CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53

21 January 2018

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Nucleophosmin regulates the stability and transcriptional activity of p53

21 January 2018

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Stress-dependent nucleolin mobilization mediated by p53-nucleolin complex formation

21 January 2018

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ADP-ribosylation of p53 tumor suppressor protein: mutant but not wild-type p53 is modified

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Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses

21 January 2018

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p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

21 January 2018

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Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

21 January 2018

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Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1196/ANNALS.1299.046

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9 August 2017

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