Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection (Q35737584)

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scientific article published on December 2011

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English	Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection	scientific article published on December 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

cancer-associated fibroblast

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Federica Sotgia

11

object named as

Federica Sotgia

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Michael P. Lisanti

12

object named as

Michael P Lisanti

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Europe PubMed Central

PubMed publication ID

10 August 2017

Diana Whitaker-Menezes

7

object named as

Diana Whitaker-Menezes

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Europe PubMed Central

PubMed publication ID

10 August 2017

Richard Pestell

9

object named as

Richard G Pestell

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Europe PubMed Central

PubMed publication ID

10 August 2017

Ubaldo E Martinez-Outschoorn

5

object named as

Ubaldo E Martinez-Outschoorn

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Barbara Chiavarina

8

object named as

Barbara Chiavarina

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Europe PubMed Central

PubMed publication ID

10 August 2017

Claudia Capparelli

2

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Claudia Capparelli

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Europe PubMed Central

PubMed publication ID

10 August 2017

Renee M Balliet

1

object named as

Renee M Balliet

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Timothy G Pestell

4

object named as

Timothy G Pestell

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Europe PubMed Central

PubMed publication ID

10 August 2017

10

object named as

Anthony Howell

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Europe PubMed Central

PubMed publication ID

10 August 2017

3

object named as

Carmela Guido

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

author name string

Zhao Lin

6

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Europe PubMed Central

PubMed publication ID

10 August 2017

publication date

1 December 2011

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Europe PubMed Central

PubMed publication ID

10 August 2017

number of pages

9

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PubMed publication ID

10 August 2017

10

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Europe PubMed Central

PubMed publication ID

10 August 2017

23

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Europe PubMed Central

PubMed publication ID

10 August 2017

4065-4073

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue

1 reference

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N-acetylcysteine supplementation controls total antioxidant capacity, creatine kinase, lactate, and tumor necrotic factor-alpha against oxidative stress induced by graded exercise in sedentary men.

1 reference

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Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis

1 reference

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Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

1 reference

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Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

1 reference

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Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".

1 reference

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Mitochondrial targeted catalase suppresses invasive breast cancer in mice.

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Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

1 reference

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Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers

1 reference

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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

1 reference

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Otto Warburg's contributions to current concepts of cancer metabolism

1 reference

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Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment

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Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal

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Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts

1 reference

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HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

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The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

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Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

1 reference

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Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

1 reference

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12 July 2018

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

1 reference

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12 July 2018

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

1 reference

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Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling

1 reference

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12 July 2018

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors

1 reference

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Oxidative stress promotes myofibroblast differentiation and tumour spreading

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Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers

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Mitochondrial stress signals revise an old aging theory

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EXPERIMENTS ON ANAEROBIOSIS OF CANCER CELLS

1 reference

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Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.4161/CC.10.23.18254

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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