Connecting cell-cycle activation to neurodegeneration in Drosophila. (Q36671551)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17141486%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

review article

1 reference

title

Connecting cell-cycle activation to neurodegeneration in Drosophila (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17141486%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

0 references

1 reference

1

1 reference

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22 December 2019

author name string

Mel B Feany

series ordinal

2

1 reference

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22 December 2019

language of work or name

English

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publication date

18 October 2006

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Biochimica et Biophysica Acta

22 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17141486%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

1772

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22 December 2019

issue

4

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22 December 2019

page(s)

446-456

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Myc/Max/Mad in invertebrates: the evolution of the Max network

22 December 2019

cites work

1 reference

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Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1.

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Signaling and function of insulin-like peptides in insects

30 September 2017

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SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation

30 September 2017

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Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

30 September 2017

1 reference

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Myc, cell competition, and compensatory proliferation

30 September 2017

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Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

30 September 2017

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Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease

30 September 2017

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To die or grow: Parkinson's disease and cancer

30 September 2017

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Drosophila melanogaster: a model for the study of DNA damage checkpoint response.

30 September 2017

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The E2F transcriptional network: old acquaintances with new faces

30 September 2017

1 reference

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Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

30 September 2017

1 reference

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Regulation of neuron survival and death by p130 and associated chromatin modifiers

30 September 2017

1 reference

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Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism.

30 September 2017

1 reference

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Tau and src family tyrosine kinases

30 September 2017

1 reference

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Pinning down phosphorylated tau and tauopathies

30 September 2017

1 reference

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Sir2 mediates longevity in the fly through a pathway related to calorie restriction

30 September 2017

1 reference

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mTOR: a protein kinase switching between life and death

30 September 2017

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

30 September 2017

1 reference

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The PCNA-RFC families of DNA clamps and clamp loaders

30 September 2017

1 reference

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

30 September 2017

1 reference

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RAS and RHO GTPases in G1-phase cell-cycle regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The TOR pathway: a target for cancer therapy

30 September 2017

1 reference

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Myc: a weapon of mass destruction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Alzheimer's disease: the two-hit hypothesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cell cycle regulation of neuronal apoptosis in development and disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis

30 September 2017

1 reference

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Genetics: influence of TOR kinase on lifespan in C. elegans

30 September 2017

1 reference

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Genetic modifiers of tauopathy in Drosophila.

30 September 2017

1 reference

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Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster

30 September 2017

1 reference

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Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

30 September 2017

1 reference

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Drosophila Rheb GTPase is required for cell cycle progression and cell growth

30 September 2017

1 reference

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Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

30 September 2017

1 reference

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Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

30 September 2017

1 reference

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Rheb promotes cell growth as a component of the insulin/TOR signalling network

30 September 2017

1 reference

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Oxidative stress, cell cycle, and neurodegeneration

30 September 2017

1 reference

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Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

30 September 2017

1 reference

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Tor signalling in bugs, brain and brawn

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

When parsimony backfires: neglecting DNA repair may doom neurons in Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

A revised picture of the E2F transcriptional network and RB function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Tau protein in normal and Alzheimer's disease brain.

30 September 2017

1 reference

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Akt regulates growth by directly phosphorylating Tsc2

30 September 2017

1 reference

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Cellular response to oxidative stress: signaling for suicide and survival

30 September 2017

1 reference

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Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

30 September 2017

1 reference

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Neuronal apoptosis at the G1/S cell cycle checkpoint

30 September 2017

1 reference

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Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system

30 September 2017

1 reference

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Histone H3 phosphorylation and cell division

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The Drosophila cyclin D-Cdk4 complex promotes cellular growth

30 September 2017

1 reference

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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

p21(WAF1/Cip1): more than a break to the cell cycle?

30 September 2017

1 reference

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The genome sequence of Drosophila melanogaster

30 September 2017

1 reference

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The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The role of c-myc in cellular growth control

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The regulation of E2F by pRB-family proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Tau complexes with phospholipase C-gamma in situ

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Developmental control of cell cycle regulators: a fly's perspective

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Activation of phospholipase C-gamma by the concerted action of tau proteins and arachidonic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cell death and the cell cycle: a relationship between transformation and neurodegeneration?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Effects of an Rb mutation in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Role of oxidative stress in Drosophila aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear pa

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The neuroendocrine regulation of Drosophila aging

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Extra-embryonic function of Rb is essential for embryonic development and viability

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Developmental biology: A twist in a mouse tale.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Phosphorylated c-MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

DNA replication precedes neuronal cell death in Alzheimer's disease.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562667

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

20 September 2018

1 reference

12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

12 December 2020

Ras1 promotes cellular growth in the Drosophila wing

1 reference

12 December 2020

Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models

1 reference

12 December 2020

10.1016/J.BBADIS.2006.10.007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17141486%20AND%20SRC:MED&resulttype=core&format=json

release_xeiungw6yvd2xbh3z3gquzdd4u

22 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xeiungw6yvd2xbh3z3gquzdd4u

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17141486%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

17141486

1 reference