Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism (Q38662384)

5 September 2017

title

Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism (English)

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5 September 2017

1 reference

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

4

Pierre Sonveaux

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

2

Valéry L Payen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Bjorn Baselet

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

8 December 2015

1 reference

Cellular and Molecular Life Sciences

5 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

73

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

1349-1363

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

Cancer metastasis: building a framework

9 June 2020

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Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation

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Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

21 January 2018

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Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

21 January 2018

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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

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A mitochondrial switch promotes tumor metastasis.

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HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells

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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

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Adaptation of energy metabolism in breast cancer brain metastases

21 January 2018

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Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration.

21 January 2018

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Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells

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Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

21 January 2018

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BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function

21 January 2018

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Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo

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Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis.

21 January 2018

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Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

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21 January 2018

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A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species.

21 January 2018

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Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways

21 January 2018

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Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer.

21 January 2018

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Stretch-induced phosphorylation of focal adhesion kinase in endothelial cells: role of mitochondrial oxidants

21 January 2018

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

21 January 2018

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Extracellular redox status regulates Nrf2 activation through mitochondrial reactive oxygen species

21 January 2018

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

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The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

21 January 2018

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The promise and perils of antioxidants for cancer patients

21 January 2018

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Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

21 January 2018

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Learning from oncocytic tumors: Why choose inefficient mitochondria?

21 January 2018

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Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma

21 January 2018

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Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

21 January 2018

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Enhanced citrate synthase activity in human pancreatic cancer.

21 January 2018

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Citrate synthase expression affects tumor phenotype and drug resistance in human ovarian carcinoma

21 January 2018

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Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy.

21 January 2018

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Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues

21 January 2018

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Citrate enhances in vitro metastatic behaviours of PC-3M human prostate cancer cells: status of endogenous citrate and dependence on aconitase and fatty acid synthase

21 January 2018

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21 January 2018

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Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

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HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

21 January 2018

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Glutaminolysis activates Rag-mTORC1 signaling.

21 January 2018

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Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

21 January 2018

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IDH1 and IDH2 mutations in gliomas

21 January 2018

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Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production

21 January 2018

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Recurring mutations found by sequencing an acute myeloid leukemia genome

21 January 2018

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Mutant IDH is sufficient to initiate enchondromatosis in mice

21 January 2018

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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

21 January 2018

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Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9

21 January 2018

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Germline SDHD mutation in familial phaeochromocytoma

21 January 2018

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Germ-line mutations in nonsyndromic pheochromocytoma

21 January 2018

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Germline SDHB mutations and familial renal cell carcinoma.

21 January 2018

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Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations

21 January 2018

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

21 January 2018

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Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas

21 January 2018

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Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases

21 January 2018

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SDH mutations establish a hypermethylator phenotype in paraganglioma.

21 January 2018

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Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

21 January 2018

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Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress

21 January 2018

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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

21 January 2018

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An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma

21 January 2018

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism

21 January 2018

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Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion

21 January 2018

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Dimethylfumarate impairs melanoma growth and metastasis

21 January 2018

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Dimethylfumarate inhibits tumor cell invasion and metastasis by suppressing the expression and activities of matrix metalloproteinases in melanoma cells

21 January 2018

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Combination of dacarbazine and dimethylfumarate efficiently reduces melanoma lymph node metastasis

21 January 2018

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Succinate dehydrogenase 5 (SDH5) regulates glycogen synthase kinase 3β-β-catenin-mediated lung cancer metastasis

21 January 2018

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Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.

21 January 2018

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Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells

21 January 2018

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Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

21 January 2018

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Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth

21 January 2018

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Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis

21 January 2018

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Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer.

21 January 2018

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Cancer cell metabolism: Warburg and beyond

21 January 2018

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

21 January 2018

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Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigen.

21 January 2018

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Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth.

21 January 2018

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MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

21 January 2018

1 reference

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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis.

21 January 2018

1 reference

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Fatty acid synthase as a potential therapeutic target in cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

ATP citrate lyase inhibition can suppress tumor cell growth

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Expression of the lipogenic enzyme fatty acid synthase (FAS) in retinoblastoma and its correlation with tumor aggressiveness

21 January 2018

1 reference

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Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Interchange of amino acids between tumor and host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.

21 January 2018

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

21 January 2018

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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

21 January 2018

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Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Plasma free amino acid profiling of five types of cancer patients and its application for early detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

A trypsin-like neutral protease on Ehrlich ascites cell surfaces: its role in the activation of tumour-cell zymogen of collagenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Expression of indoleamine 2,3-dioxygenase and infiltration of FOXP3+ regulatory T cells are associated with aggressive features of papillary thyroid microcarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2100-2

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

21 January 2018

1 reference

12 December 2020

Glutamine metabolism in AS-30D hepatoma cells. Evidence for its conversion into lipids via reductive carboxylation

1 reference

12 December 2020

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

1 reference

12 December 2020

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

1 reference

12 December 2020

Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients

1 reference

12 December 2020

Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide.

1 reference

12 December 2020

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

1 reference

12 December 2020

1 reference

12 December 2020

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

1 reference

12 December 2020

Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis

1 reference

12 December 2020

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

1 reference

12 December 2020

Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families

1 reference

12 December 2020

Production of large amounts of hydrogen peroxide by human tumor cells

1 reference

12 December 2020

10.1007/S00018-015-2100-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json

release_gmbnr6mp6nar3fal573xhtwwqa

9 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gmbnr6mp6nar3fal573xhtwwqa

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26646069%20AND%20SRC:MED&resulttype=core&format=json