BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization (Q42598140)

3 November 2017

title

BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization (English)

1 reference

3 November 2017

BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

28 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

28 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

28 December 2023

author name string

Salvatore C. Ruffolo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12721291

28 December 2023

Gordon C. Shore

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12721291

28 December 2023

language of work or name

English

0 references

publication date

29 April 2003

1 reference

full work available at URL

3 November 2017

http://www.jbc.org/content/278/27/25039.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12721291

https://api.elsevier.com/content/article/PII:S0021925820869683?httpAccept=text/xml

28 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

https://api.elsevier.com/content/article/PII:S0021925820869683?httpAccept=text/plain

28 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

https://syndication.highwire.org/content/doi/10.1074/jbc.M302930200

28 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

Journal of Biological Chemistry

28 December 2023

published in

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3 November 2017

volume

278

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3 November 2017

issue

27

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3 November 2017

page(s)

25039-25045

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

3 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Regulated targeting of BAX to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

The apoptotic protein tBid promotes leakage by altering membrane curvature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Solution structure of BID, an intracellular amplifier of apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Bak and Bax function to limit adenovirus replication through apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302930200

21 January 2018

The roles of Bid

11

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

PUMA induces the rapid apoptosis of colorectal cancer cells

28 December 2023

17

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

BID-dependent and BID-independent pathways for BAX insertion into mitochondria

28 December 2023

32

1 reference

https://api.crossref.org/works/10.1074/JBC.M302930200

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

28 December 2023

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https://api.crossref.org/works/10.1074/JBC.M302930200

28 December 2023

Identifiers

1 reference

3 November 2017

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