Hierarchical modularity and the evolution of genetic interactomes across species. (Q27932016)

PubMed

22681890

1 December 2016

title

Hierarchical modularity and the evolution of genetic interactomes across species. (English)

1 reference

PubMed

1 December 2016

0 references

1 reference

Ubiquitin-protein ligase TUL1 YKL034W

1 reference

Dsc2p YOL073C

1 reference

Dsc3p YOR223W

1 reference

Michael-Christopher Keogh

author

17

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Colm J. Ryan

Colm J Ryan

1

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Sean R Collins

Sean R Collins

10

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J Peter Svensson

J Peter Svensson

23

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Pedro Beltrao

Pedro Beltrao

7

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Gerard Cagney

Gerard Cagney

22

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Joseph I Kliegman

Joseph I Kliegman

11

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Trey Ideker

26

Trey Ideker

0 references

Padraig Cunningham

20

Pádraig Cunningham

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Nevan Krogan

27

Nevan J Krogan

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author name string

Assen Roguev

2

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Kristin Patrick

3

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Jiewei Xu

4

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Harlizawati Jahari

5

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Zongtian Tong

6

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Michael Shales

8

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Hong Qu

9

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Lingli Jiang

12

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Dwight Kuo

13

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Elena Tosti

14

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Hyun-Soo Kim

15

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Winfried Edelmann

16

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Derek Greene

18

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Chao Tang

19

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Kevan M Shokat

21

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Christine Guthrie

24

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Peter J Espenshade

25

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language of work or name

English

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publication date

8 June 2012

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1 reference

22681890

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

1 December 2016

volume

46

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issue

5

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page(s)

691-704

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cites work

1 reference

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A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling

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Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function

20 March 2017

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20 March 2017

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Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex

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Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription

20 March 2017

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A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

20 March 2017

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Global mapping of the yeast genetic interaction network

20 March 2017

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A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

20 March 2017

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ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

20 March 2017

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20 March 2017

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Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

20 March 2017

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The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program

20 March 2017

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Where does fission yeast sit on the tree of life?

20 March 2017

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20 March 2017

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pICln inhibits snRNP biogenesis by binding core spliceosomal proteins

20 March 2017

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Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure

20 March 2017

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20 March 2017

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The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex

20 March 2017

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20 March 2017

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Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways

20 March 2017

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20 March 2017

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20 March 2017

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7 April 2017

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7 April 2017

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29 September 2017

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29 September 2017

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Improved functional overview of protein complexes using inferred epistatic relationships.

29 September 2017

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Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

29 September 2017

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Mapping of signaling networks through synthetic genetic interaction analysis by RNAi

29 September 2017

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Novel genes exhibit distinct patterns of function acquisition and network integration

29 September 2017

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Rewiring of genetic networks in response to DNA damage.

29 September 2017

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Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

29 September 2017

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Epistatic relationships reveal the functional organization of yeast transcription factors

29 September 2017

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Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

29 September 2017

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Genome-wide association data reveal a global map of genetic interactions among protein complexes

29 September 2017

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HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles

29 September 2017

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29 September 2017

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29 September 2017

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The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.

29 September 2017

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29 September 2017

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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

29 September 2017

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Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.

29 September 2017

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29 September 2017

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Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases

29 September 2017

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Functional maps of protein complexes from quantitative genetic interaction data

29 September 2017

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The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

29 September 2017

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A global analysis of genetic interactions in Caenorhabditis elegans

29 September 2017

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High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe

29 September 2017

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Modelling genotype-phenotype relationships and human disease with genetic interaction networks

29 September 2017

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Transcriptional regulation of protein complexes within and across species

29 September 2017

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A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

29 September 2017

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Modeling cellular machinery through biological network comparison

29 September 2017

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The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast

29 September 2017

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Systematic interpretation of genetic interactions using protein networks

29 September 2017

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Conserved patterns of protein interaction in multiple species

29 September 2017

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The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

29 September 2017

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Conserved pathways within bacteria and yeast as revealed by global protein network alignment

29 September 2017

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The evolutionary analysis of "orphans" from the Drosophila genome identifies rapidly diverging and incorrectly annotated genes

29 September 2017

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Quantitative genetic interaction mapping using the E-MAP approach

29 September 2017

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Quantitative genetic interactions reveal biological modularity

2 June 2018

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Optimal stepwise experimental design for pairwise functional interaction studies

2 June 2018

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LAMMER kinase Kic1 is involved in pre-mRNA processing.

2 June 2018

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Violations of robustness trade-offs

27 November 2018

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Evolutionary plasticity of genetic interaction networks

27 November 2018

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Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

27 November 2018

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Vacuolar protein sorting receptor in Schizosaccharomyces pombe

27 November 2018

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Epistasis: too often neglected in complex trait studies?

27 November 2018

1 reference

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Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A.

27 November 2018

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10.1016/J.MOLCEL.2012.05.028

27 November 2018

Identifiers

DOI

1 reference

1 reference

1 reference

22681890

1 reference