From nucleation to widespread propagation: A prion-like concept for ALS. (Q38345753)

2 September 2017

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title

From nucleation to widespread propagation: A prion-like concept for ALS. (English)

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amyotrophic lateral sclerosis

2 September 2017

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Zuzanna Maniecka

1

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2 September 2017

Magdalini Polymenidou

series ordinal

2

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2 September 2017

publication date

2 February 2015

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2 September 2017

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2 September 2017

volume

207

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2 September 2017

page(s)

94-105

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Beyond the prion principle

2 September 2017

cites work

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Premorbid weight, body mass, and varsity athletics in ALS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

An MND/ALS phenotype associated with C9orf72 repeat expansion: abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Physical activity and the association with sporadic ALS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Astrocytic TDP-43 pathology in Alexander disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Generating a prion with bacterially expressed recombinant prion protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Prospective study of military service and mortality from ALS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Regulated protein aggregation: stress granules and neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Frameshift and novel mutations in FUS in familial amyotrophic lateral sclerosis and ALS/dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

TDP-43 mutation in familial amyotrophic lateral sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

Non-ATG-initiated translation directed by microsatellite expansions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2014.12.032

10.1016/J.VIRUSRES.2014.12.032

7 January 2021

Identifiers

DOI

1 reference

2 September 2017

1 reference